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By shaping these pathways, TB-500 appears to offer researchers a model for examining potential anti-inflammatory mechanisms and their regulation

Published rodent oral protocols have used 10-50 mcg/kg/day

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By selectively inhibiting NNMT an enzyme central to energy regulation and fat metabolism this compound has demonstrated, in preclinical studies, the capacity to elevate intracellular NAD and SAM levels, suppress lipid accumulation in adipocytes, and reduce white adipose tissue mass in diet-induced obese mouse models